Most of us are attempting to avoid contracting the COVID-19 Virus by using masks, gloves, disinfectants, and antiseptics. Shouldn’t we also focus on strengthening our body’s immune system? There is more than one strain of Coronavirus. However, the following analysis generally applies.
Boost Immune System – Enhancing Your Body’s Ability to Fight the COVID-19 Virus with EFAs Including Appendix Detailing How Essential EFAs are Related to Killing Viral-Relating Diseases / Conditions
– By Professor Brian Peskin*
Most of us are attempting to avoid contracting the COVID-19 Virus by using masks, gloves, disinfectants, and antiseptics. Shouldn’t we also focus on strengthening our body’s immune system? There is more than one strain of Corona virus. However, the following analysis generally applies. “Inactivation of Enveloped Viruses and Killing of Cells by Fatty Acids,” and 2019’s “Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication,” specify that the long chain fatty acids; in particular, Parent omega-6 and its long chain metabolite AA can destroy the virus at the cellular level.
I thank my colleague, EFA/eicosanoid specialist Paul Beatty, from Toronto, Canada for providing these articles presented here and many of the references in the Appendices.
Today, due to food processing—unless you are consuming organic Parent omega-6 —it will be adulterated and inactive to a large extent. For optimal protection, an Essential Fatty Acids (EFA) formulation should optimize cell membrane structure (viruses must bind and join the cell’s membrane) and maximize blood flow. EFAs must be consumed on a daily basis.
We all understand that a strong immune system is key to staying healthy. Parent omega-6 also optimizes cellular health by flooding each of your cells with oxygen. Please understand this review of two important journal articles assumes you understand the basis of my work for the last twenty years. Specifically, that our daily diet unfortunately consists of a variety of adulterated oils. You must offset this damage by supplementing with unadulterated oils, specifically Parent Omega6 and Parent Omega-3. Therefore, when I reference Omega-6 and Omega-3, unless otherwise noted, it is fully functional and unadulterated.
In an effort to assist you, I have summarized these two articles:
The 1st article analyzed nine fatty acids found in human breast milk for their anti-viral effect.
Enveloped viruses like the Corona Virus are susceptible to inactivation and destruction by certain fatty acids. This journal article study makes clear that all fats are not equal in anti-viral effectiveness — only (unprocessed / fully functional) medium-chain saturated, and long-chain unsaturated fatty acids were antiviral (but at varying concentrations):
• “The polyunsaturated long-chain fatty acids [like PEOs] were the most active and effective antiviral in killing enveloped viruses.
• “Antiviral fatty acids were found to affect the viral envelope, causing leakage and at higher concentrations, a complete disintegration of the envelope and the viral particles. They also caused disintegration of the plasma membranes of tissue culture cells resulting in cell lysis and death….
The 2nd article analyzed 24 lipids. There are several pathogenic Corona virus types similar to the current 2019-nCoV and the researchers looked at the highly pathogenic MERS corona virus — which had an enormous 34% mortality rate. LA [Parent omega-6] is the metabolic precursor of AA — both of which are key components of the cell membrane and biological signaling precursors.
Researchers found that optimal corona virus replication required a specific composition of cellular lipids and any disruption could decrease the efficiency of corona virus replication:
• Supplementation of LA [Parent omega-6] / AA [omega-6 series long-chain derivative] significantly suppressed both HCoV-229E (which can impair the respiratory system), and also significantly suppressed the highly virulent MERS-CoV described above. They can be metabolized to important eicosanoids and metabolites, which play multiple roles in the host immune response and the pathogenesis of viral infections.
• “LA metabolism and AA metabolism pathways presented higher impact than the other pathways. Our data demonstrated that LA and AA potently suppressed MERS-CoV replication in a similar manner as HCoV-229E. Overall, our results demonstrated that exogenously supplied [from a supplement] LA and AA could interfere with the optimal replication of human-pathogenic corona viruses….”
Essential EFAs are known to limit this excessive over reactive cytokine reaction:
“Essential fatty acids are natural anti-inflammatory agents and therefore decrease the production of cytokines and histamine, which can contribute to neurotransmitter imbalance (from the “ESSENTIAL FATTY ACIDS chapter of the book, Integrative Medicine for Children, 2009).” Because EFAs work so well to kill viruses, and boost immune system it is worthwhile to review the medical literature regarding other viral-related disorders in the Appendices below. Engineering often makes great use of past discoveries. Tragically, at least in the lipids area, modern medicine often fails to make use of significant undisputable past discoveries. To forward the Essential EFA/anti-viral connection, we will remedy that deficiency in the following appendices: [Note: For completeness, there is a high level of technicality that cannot be avoided.]
APPENDICES:
Dr. Horrobin, noted authority on EFAs and eicosanoids has written a most significant medical journal article [DF. Horrobin (1990) Essential Fatty Acids, Immunity and Viral Infections, Journal of Nutritional Medicine, 1:2, 145-151]:
“There is evidence of a close interrelationship between essential fatty acid (EFA) metabolism and the ability to respond to viral infections. EFAs are required to enable interferon to exert its antiviral effects. Viral infections both in vivo and in vitro induce abnormalities of EFA metabolism.
In a placebo controlled study in post-viral fatigue syndrome EFA supplementation with n-3 and n-6 EFAs has been found effective in reversing the plasma EFA abnormalities and treating the clinical state. These observations suggest that normal EFA metabolism is of major importance in regulating the response to viral infections and boost immune system.”
To read the full Article in PDF format
DOWNLOAD* Brian Peskin received an appointment as an Adjunct Professor at Texas Southern University in the Department of Pharmacy and Health Sciences (1998-1999).
MORE GREAT ARTICLES
The Truth About Fish Oils